SIGLEC family-like protein 1 (SIGLECL1)
Homo sapiens — UniProt Q8N7X8
Data last refreshed: (UniProt release unknown)
Key facts
SIGLEC family-like protein 1 (SIGLECL1) is a protein from Homo sapiens identified by UniProt accession Q8N7X8, 197 residues long. MolForge cross-references it against 0 known binders and 9 disease associations.
- UniProt accession: Q8N7X8; gene symbol SIGLECL1.
- Organism: Homo sapiens.
- Length: 197 amino acids.
- Top disease associations (Open Targets): myeloid white cell count, blood protein measurement and body height.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | SIGLEC family-like protein 1 |
|---|---|
| UniProt accession | Q8N7X8 |
| Gene | SIGLECL1 |
| Organism | Homo sapiens |
| Length | 197 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (9)
Diseases linked to this target (Open Targets).
- myeloid white cell count · score 0.32
- blood protein measurement · score 0.26
- body height · score 0.23
- HbA1c measurement · score 0.23
- diet measurement · score 0.20
- body mass index · score 0.17
- leukocyte count · score 0.04
- platelet crit · score 0.03
- myeloid cell surface antigen CD33 measurement · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N7X8-F1 | alphafold | PREDICTED | 83.22 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N7X8.
Amino-acid sequence (197 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SIGLECL1?
The strongest Open Targets associations for SIGLECL1 are myeloid white cell count, blood protein measurement, body height, HbA1c measurement and diet measurement.
How long is the SIGLECL1 protein?
The Homo sapiens SIGLECL1 protein (UniProt Q8N7X8) is 197 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N7X8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N7X8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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