Proline-rich protein 23E (PRR23E)
Homo sapiens — UniProt Q8N813
Data last refreshed: (UniProt release unknown)
Key facts
Proline-rich protein 23E (PRR23E) is a protein from Homo sapiens identified by UniProt accession Q8N813, 242 residues long. MolForge cross-references it against 0 known binders and 13 disease associations.
- UniProt accession: Q8N813; gene symbol PRR23E.
- Organism: Homo sapiens.
- Length: 242 amino acids.
- Top disease associations (Open Targets): self reported educational attainment, 5-oxoproline measurement and intelligence.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Proline-rich protein 23E |
|---|---|
| UniProt accession | Q8N813 |
| Gene | PRR23E |
| Organism | Homo sapiens |
| Length | 242 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (13)
Diseases linked to this target (Open Targets).
- self reported educational attainment · score 0.08
- 5-oxoproline measurement · score 0.07
- intelligence · score 0.07
- mathematical ability · score 0.07
- myotonic syndrome · score 0.06
- risk-taking behaviour · score 0.06
- schizophrenia · score 0.05
- cortical surface area measurement · score 0.05
- cognitive function measurement · score 0.05
- colon adenocarcinoma · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N813-F1 | alphafold | PREDICTED | 46.88 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N813.
Amino-acid sequence (242 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PRR23E?
The strongest Open Targets associations for PRR23E are self reported educational attainment, 5-oxoproline measurement, intelligence, mathematical ability and myotonic syndrome.
How long is the PRR23E protein?
The Homo sapiens PRR23E protein (UniProt Q8N813) is 242 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N813 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N813 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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