Zinc finger protein 611 (ZNF611)

About Zinc finger protein 611

Zinc finger protein 611 (ZNF611) is a protein from Homo sapiens identified by UniProt accession Q8N823, 705 residues long. MolForge cross-references it against 0 known binders and 25 disease associations.

Target properties

Protein name	Zinc finger protein 611
UniProt accession	Q8N823
Gene	ZNF611
Organism	Homo sapiens
Length	705 residues
Molecular weight	—
EC numbers	—
Target class	—
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (25)

Diseases linked to this target (Open Targets).

Red cell distribution width · score 0.30
genetic disorder · score 0.12
Shwachman-Diamond syndrome · score 0.03
atypical hemolytic-uremic syndrome with C3 anomaly · score 0.03
atypical hemolytic-uremic syndrome with MCP/CD46 anomaly · score 0.03
atypical hemolytic-uremic syndrome with I factor anomaly · score 0.03
atypical hemolytic-uremic syndrome with thrombomodulin anomaly · score 0.03
Blackfan-Diamond anemia · score 0.03
tubulointerstitial kidney disease, autosomal dominant, 2 · score 0.03
atypical hemolytic-uremic syndrome with B factor anomaly · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8N823-F1	alphafold	PREDICTED	64.15	—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N823.

Amino-acid sequence (705 residues)

MLREEAAQKR KGKEPGMALP QGRLTFRDVA IEFSLAEWKC LNPSQRALYR EVMLENYRNL EAVDISSKCM MKEVLSTGQG NTEVIHTGTL QRHESHHIGD FCFQEIEKEI HDIEFQCQED ERNGLEAPMT KIKKLTGSTD QHDHRHAGNK PIKDQLGSSF YSHLPELHIF QIKGEIGNQL EKSTNDAPSV STFQRISCRP QTQISNNYGN NPLNSSLLPQ KQEVHMREKS FQCNKSGKAF NCSSLLRKHQ IPHLGDKQYK CDVCGKLFNH EQYLACHDRC HTVEKPYKCK ECGKTFSQES SLTCHRRLHT GVKRYNCNEC GKIFGQNSAL LIDKAIDTGE NPYKCNECDK AFNQQSQLSH HRIHTGEKPY KCEECDKVFS RKSTIETHKR IHTGEKPYRC KVCDTAFTWH SQLARHRRIH TAKKTYKCNE CGKTFSHKSS LVCHHRLHGG EKSYKCKVCD KAFVWSSQLA KHTRIDCGEK PYKCNECGKT FGQNSDLLIH KSIHTGEQPY KCDECEKVFS RKSSLETHKI GHTGEKPYKC KVCDKAFACH SYLAKHTRIH SGEKPYKCNE CSKTFSHRSY LVCHHRVHSG EKPYKCNECS KTFSRRSSLH CHRRLHSGEK PYKCNECGNT FRHCSSLIYH RRLHTGEKSY KCTICDKAFV RNSLLSRHTR IHTAEKPYKC NECGKAFNQQ SHLSRHHRIH TGEKP

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards