Zinc finger protein 611 (ZNF611)
Homo sapiens — UniProt Q8N823
Data last refreshed: (UniProt release unknown)
Key facts
Zinc finger protein 611 (ZNF611) is a protein from Homo sapiens identified by UniProt accession Q8N823, 705 residues long. MolForge cross-references it against 0 known binders and 25 disease associations.
- UniProt accession: Q8N823; gene symbol ZNF611.
- Organism: Homo sapiens.
- Length: 705 amino acids.
- Top disease associations (Open Targets): Red cell distribution width, genetic disorder and Shwachman-Diamond syndrome.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc finger protein 611 |
|---|---|
| UniProt accession | Q8N823 |
| Gene | ZNF611 |
| Organism | Homo sapiens |
| Length | 705 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (25)
Diseases linked to this target (Open Targets).
- Red cell distribution width · score 0.30
- genetic disorder · score 0.12
- Shwachman-Diamond syndrome · score 0.03
- atypical hemolytic-uremic syndrome with C3 anomaly · score 0.03
- atypical hemolytic-uremic syndrome with MCP/CD46 anomaly · score 0.03
- atypical hemolytic-uremic syndrome with I factor anomaly · score 0.03
- atypical hemolytic-uremic syndrome with thrombomodulin anomaly · score 0.03
- Blackfan-Diamond anemia · score 0.03
- tubulointerstitial kidney disease, autosomal dominant, 2 · score 0.03
- atypical hemolytic-uremic syndrome with B factor anomaly · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N823-F1 | alphafold | PREDICTED | 64.15 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N823.
Amino-acid sequence (705 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZNF611?
The strongest Open Targets associations for ZNF611 are Red cell distribution width, genetic disorder, Shwachman-Diamond syndrome, atypical hemolytic-uremic syndrome with C3 anomaly and atypical hemolytic-uremic syndrome with MCP/CD46 anomaly.
How long is the ZNF611 protein?
The Homo sapiens ZNF611 protein (UniProt Q8N823) is 705 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N823 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N823 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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