Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B (ANKRD44)
Homo sapiens — UniProt Q8N8A2
Data last refreshed: (UniProt release unknown)
Key facts
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B (ANKRD44) is a protein from Homo sapiens identified by UniProt accession Q8N8A2, 993 residues long. MolForge cross-references it against 0 known binders and 71 disease associations.
- UniProt accession: Q8N8A2; gene symbol ANKRD44.
- Organism: Homo sapiens.
- Length: 993 amino acids.
- Top disease associations (Open Targets): body fat percentage, schizophrenia and adolescent idiopathic scoliosis.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B |
|---|---|
| UniProt accession | Q8N8A2 |
| Gene | ANKRD44 |
| Organism | Homo sapiens |
| Length | 993 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (71)
Diseases linked to this target (Open Targets).
- body fat percentage · score 0.41
- schizophrenia · score 0.31
- adolescent idiopathic scoliosis · score 0.30
- body height · score 0.29
- anorexia nervosa · score 0.28
- serum alanine aminotransferase measurement · score 0.28
- low density lipoprotein triglyceride measurement · score 0.28
- sex hormone-binding globulin measurement · score 0.28
- high density lipoprotein cholesterol measurement · score 0.28
- aspartate aminotransferase measurement · score 0.28
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N8A2-F1 | alphafold | PREDICTED | 90.58 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N8A2.
Amino-acid sequence (993 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ANKRD44?
The strongest Open Targets associations for ANKRD44 are body fat percentage, schizophrenia, adolescent idiopathic scoliosis, body height and anorexia nervosa.
How long is the ANKRD44 protein?
The Homo sapiens ANKRD44 protein (UniProt Q8N8A2) is 993 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N8A2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N8A2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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