ATP-dependent RNA helicase DDX51 (DDX51)
Homo sapiens — UniProt Q8N8A6
Data last refreshed: (UniProt release unknown)
Key facts
ATP-dependent RNA helicase DDX51 (DDX51) is a protein from Homo sapiens identified by UniProt accession Q8N8A6, 666 residues long. MolForge cross-references it against 0 known binders and 25 disease associations.
- UniProt accession: Q8N8A6; gene symbol DDX51.
- Organism: Homo sapiens.
- Length: 666 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, body height and mean corpuscular volume.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | ATP-dependent RNA helicase DDX51 |
|---|---|
| UniProt accession | Q8N8A6 |
| Gene | DDX51 |
| Organism | Homo sapiens |
| Length | 666 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (25)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.44
- body height · score 0.29
- mean corpuscular volume · score 0.24
- mean corpuscular hemoglobin concentration · score 0.23
- sitting height measurement · score 0.21
- appendicular lean mass · score 0.20
- lean body mass · score 0.20
- mean reticulocyte volume · score 0.08
- whole body water mass · score 0.08
- base metabolic rate measurement · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N8A6-F1 | alphafold | PREDICTED | 73.54 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N8A6.
Amino-acid sequence (666 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with DDX51?
The strongest Open Targets associations for DDX51 are neurodegenerative disease, body height, mean corpuscular volume, mean corpuscular hemoglobin concentration and sitting height measurement.
How long is the DDX51 protein?
The Homo sapiens DDX51 protein (UniProt Q8N8A6) is 666 amino acids long.
Browse: Targets: D · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N8A6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N8A6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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