Programmed cell death protein 7 (PDCD7)
Homo sapiens — UniProt Q8N8D1
Data last refreshed: (UniProt release unknown)
Key facts
Programmed cell death protein 7 (PDCD7) is a protein from Homo sapiens identified by UniProt accession Q8N8D1, 485 residues long. MolForge cross-references it against 0 known binders and 66 disease associations.
- UniProt accession: Q8N8D1; gene symbol PDCD7.
- Organism: Homo sapiens.
- Length: 485 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, acute myeloid leukemia and microphthalmia.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Programmed cell death protein 7 |
|---|---|
| UniProt accession | Q8N8D1 |
| Gene | PDCD7 |
| Organism | Homo sapiens |
| Length | 485 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (66)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.54
- acute myeloid leukemia · score 0.08
- microphthalmia · score 0.06
- nanophthalmos 2 · score 0.05
- nanophthalmia · score 0.05
- dehydrated hereditary stomatocytosis · score 0.05
- Isolated anophthalmia - microphthalmia · score 0.04
- Microphthalmia - ankyloblepharon - intellectual disability · score 0.04
- sideroblastic anemia 3 · score 0.04
- Congenital dyserythropoietic anemia type I · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N8D1-F1 | alphafold | PREDICTED | 76.43 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N8D1.
Amino-acid sequence (485 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PDCD7?
The strongest Open Targets associations for PDCD7 are neurodegenerative disease, acute myeloid leukemia, microphthalmia, nanophthalmos 2 and nanophthalmia.
How long is the PDCD7 protein?
The Homo sapiens PDCD7 protein (UniProt Q8N8D1) is 485 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N8D1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N8D1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.