Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 3 (NKAIN3)
Homo sapiens — UniProt Q8N8D7
Data last refreshed: (UniProt release unknown)
Key facts
Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 3 (NKAIN3) is a protein from Homo sapiens identified by UniProt accession Q8N8D7, 197 residues long. MolForge cross-references it against 0 known binders and 26 disease associations.
- UniProt accession: Q8N8D7; gene symbol NKAIN3.
- Organism: Homo sapiens.
- Length: 197 amino acids.
- Top disease associations (Open Targets): reading and spelling ability, blood protein measurement and Abdominal pain.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 3 |
|---|---|
| UniProt accession | Q8N8D7 |
| Gene | NKAIN3 |
| Organism | Homo sapiens |
| Length | 197 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (26)
Diseases linked to this target (Open Targets).
- reading and spelling ability · score 0.31
- blood protein measurement · score 0.17
- Abdominal pain · score 0.14
- hemoglobin measurement · score 0.13
- monocyte percentage of leukocytes · score 0.09
- calcium measurement · score 0.07
- non-small cell lung carcinoma · score 0.01
- post-traumatic stress disorder · score 0.01
- esophageal squamous cell carcinoma · score 0.01
- large cell medulloblastoma · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N8D7-F1 | alphafold | PREDICTED | 76.79 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N8D7.
Amino-acid sequence (197 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with NKAIN3?
The strongest Open Targets associations for NKAIN3 are reading and spelling ability, blood protein measurement, Abdominal pain, hemoglobin measurement and monocyte percentage of leukocytes.
How long is the NKAIN3 protein?
The Homo sapiens NKAIN3 protein (UniProt Q8N8D7) is 197 amino acids long.
Browse: Targets: N · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N8D7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N8D7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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