Zinc finger protein 513 (ZNF513)
Homo sapiens — UniProt Q8N8E2
Data last refreshed: (UniProt release unknown)
Key facts
Zinc finger protein 513 (ZNF513) is a protein from Homo sapiens identified by UniProt accession Q8N8E2, 541 residues long. MolForge cross-references it against 0 known binders and 151 disease associations.
- UniProt accession: Q8N8E2; gene symbol ZNF513.
- Organism: Homo sapiens.
- Length: 541 amino acids.
- Top disease associations (Open Targets): retinitis pigmentosa, neurodegenerative disease and autosomal dominant retinitis pigmentosa.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc finger protein 513 |
|---|---|
| UniProt accession | Q8N8E2 |
| Gene | ZNF513 |
| Organism | Homo sapiens |
| Length | 541 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (151)
Diseases linked to this target (Open Targets).
- retinitis pigmentosa · score 0.54
- neurodegenerative disease · score 0.49
- autosomal dominant retinitis pigmentosa · score 0.19
- Retinal dystrophy · score 0.19
- appendicular lean mass · score 0.18
- triglyceride measurement · score 0.15
- type 2 diabetes mellitus · score 0.15
- low density lipoprotein cholesterol measurement · score 0.15
- alcohol consumption measurement · score 0.14
- blood protein measurement · score 0.14
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N8E2-F1 | alphafold | PREDICTED | 58.82 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N8E2.
Amino-acid sequence (541 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZNF513?
The strongest Open Targets associations for ZNF513 are retinitis pigmentosa, neurodegenerative disease, autosomal dominant retinitis pigmentosa, Retinal dystrophy and appendicular lean mass.
How long is the ZNF513 protein?
The Homo sapiens ZNF513 protein (UniProt Q8N8E2) is 541 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N8E2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N8E2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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