Zinc finger protein 615 (ZNF615)
Homo sapiens — UniProt Q8N8J6
Data last refreshed: (UniProt release unknown)
Key facts
Zinc finger protein 615 (ZNF615) is a protein from Homo sapiens identified by UniProt accession Q8N8J6, 731 residues long. MolForge cross-references it against 0 known binders and 27 disease associations.
- UniProt accession: Q8N8J6; gene symbol ZNF615.
- Organism: Homo sapiens.
- Length: 731 amino acids.
- Top disease associations (Open Targets): Alzheimer disease, Parkinson disease and lysosomal storage disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc finger protein 615 |
|---|---|
| UniProt accession | Q8N8J6 |
| Gene | ZNF615 |
| Organism | Homo sapiens |
| Length | 731 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (27)
Diseases linked to this target (Open Targets).
- Alzheimer disease · score 0.27
- Parkinson disease · score 0.27
- lysosomal storage disease · score 0.27
- neurodegenerative disease · score 0.27
- multiple sclerosis · score 0.27
- pancreatic adenocarcinoma · score 0.14
- response to corticosteroid · score 0.09
- response to bronchodilator · score 0.09
- Shwachman-Diamond syndrome · score 0.03
- atypical hemolytic-uremic syndrome with C3 anomaly · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N8J6-F1 | alphafold | PREDICTED | 74.18 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N8J6.
Amino-acid sequence (731 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZNF615?
The strongest Open Targets associations for ZNF615 are Alzheimer disease, Parkinson disease, lysosomal storage disease, neurodegenerative disease and multiple sclerosis.
How long is the ZNF615 protein?
The Homo sapiens ZNF615 protein (UniProt Q8N8J6) is 731 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N8J6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N8J6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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