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Uncharacterized protein KIAA1958 (KIAA1958)

Homo sapiens — UniProt Q8N8K9

Gene: KIAA1958Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Uncharacterized protein KIAA1958 (KIAA1958) is a protein from Homo sapiens identified by UniProt accession Q8N8K9, 716 residues long. MolForge cross-references it against 0 known binders and 27 disease associations.

  • UniProt accession: Q8N8K9; gene symbol KIAA1958.
  • Organism: Homo sapiens.
  • Length: 716 amino acids.
  • Top disease associations (Open Targets): body height, hip bone size and hip bone mineral density.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameUncharacterized protein KIAA1958
UniProt accessionQ8N8K9
GeneKIAA1958
OrganismHomo sapiens
Length716 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (27)

Diseases linked to this target (Open Targets).

  • body height · score 0.21
  • hip bone size · score 0.15
  • hip bone mineral density · score 0.15
  • chronotype measurement · score 0.12
  • hypertriglyceridemia 2 · score 0.07
  • cholesterol-ester transfer protein deficiency · score 0.06
  • thyroid hormone metabolism, abnormal, 2 · score 0.05
  • sitosterolemia · score 0.05
  • Combined hyperlipidemia · score 0.05
  • homozygous familial hypercholesterolemia · score 0.05

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q8N8K9-F1alphafoldPREDICTED59.50—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N8K9.

Amino-acid sequence (716 residues)

MEDCLHTSSE NLSKLVSWAH SHGTICSLIP NLKHLLSEGS HGNLTAMWGC SAGHAYHWPL TATCRAGSQE RVCFQDNRSF NSDSPSIIGV PSETQTSPVE RYPGRPVKAK LDCNRTRDSC DFSYCSEPSE LDETVEEYED ENTLFDMVCE SSVTDEDSDF EPQTQRPQSI ARKRPGVVPS SLHSSSQTQM VDECSNDVII KKIKQEIPED YYIVANAELT GGVDGPALSL TQMAKPKPQT HAGPSCVGSA KLIPHVTSAI STELDPHGMS ASPSVISRPI VQKTARVSLA SPNRGPPGTH GTNQQVAMQM PVSTSHPNKQ ISIPLSALQL PGQDEQVASE EFLSHLPSQV SSCEVALSPS VNTEPEVSSS QQQPPVAPAI TTEATAQCIP AYSTKLNKFP VFNINDDLND LCTSAVSPNT TKATRYALNV WRYWCMTNGL KDHTDITKIP AVKLNELLEN FYVTVKKSDG SDFLATSLHA IRRGLDRILK NAGVGFSITS STFSSSTKKL KEKLWVLSKA GMSGARSRNI VYFSLSDEEE MWQAGCLGDD SPITLLSTVV KYNSQYLNMR TLQEHADLMY GDIELLKDPQ NQPYFARTDS VKRESRSGST RVCHGKIYHE HSRGHKQCPY CLLYKYMYIH RPPTQMEAKS PFYLTARKEA TDMGSVWYEE QRMGLRSLRG IVPNLAKKVK LENCENFTFV SFTQVSRRLG SHSCCQ

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with KIAA1958?

The strongest Open Targets associations for KIAA1958 are body height, hip bone size, hip bone mineral density, chronotype measurement and hypertriglyceridemia 2.

How long is the KIAA1958 protein?

The Homo sapiens KIAA1958 protein (UniProt Q8N8K9) is 716 amino acids long.

Browse: Targets: K · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ8N8K9
GeneKIAA1958
OrganismHomo sapiens
Length716
Binders0
Diseases27
View on UniProt