ADP-ribosylation factor-like protein 10 (ARL10)
Homo sapiens — UniProt Q8N8L6
Data last refreshed: (UniProt release unknown)
Key facts
ADP-ribosylation factor-like protein 10 (ARL10) is a protein from Homo sapiens identified by UniProt accession Q8N8L6, 244 residues long. MolForge cross-references it against 0 known binders and 9 disease associations.
- UniProt accession: Q8N8L6; gene symbol ARL10.
- Organism: Homo sapiens.
- Length: 244 amino acids.
- Top disease associations (Open Targets): gut microbiome measurement, Red cell distribution width and nervous system injury.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | ADP-ribosylation factor-like protein 10 |
|---|---|
| UniProt accession | Q8N8L6 |
| Gene | ARL10 |
| Organism | Homo sapiens |
| Length | 244 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (9)
Diseases linked to this target (Open Targets).
- gut microbiome measurement · score 0.22
- Red cell distribution width · score 0.07
- nervous system injury · score 0.03
- Ataxia-telangiectasia · score 0.01
- breast cancer · score 0.01
- clear cell renal carcinoma · score 0.01
- gonorrhea · score 0.00
- gastric carcinoma · score 0.00
- interstitial lung disease · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N8L6-F1 | alphafold | PREDICTED | 77.20 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N8L6.
Amino-acid sequence (244 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ARL10?
The strongest Open Targets associations for ARL10 are gut microbiome measurement, Red cell distribution width, nervous system injury, Ataxia-telangiectasia and breast cancer.
How long is the ARL10 protein?
The Homo sapiens ARL10 protein (UniProt Q8N8L6) is 244 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N8L6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N8L6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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