Prostaglandin reductase 2 (PTGR2)
Homo sapiens — UniProt Q8N8N7
Data last refreshed: (UniProt release unknown)
Key facts
Prostaglandin reductase 2 (PTGR2) is a protein from Homo sapiens identified by UniProt accession Q8N8N7, 351 residues long. MolForge cross-references it against 0 known binders and 30 disease associations.
- UniProt accession: Q8N8N7; gene symbol PTGR2.
- Organism: Homo sapiens.
- Length: 351 amino acids.
- Top disease associations (Open Targets): neuroinflammatory disorder, birth weight and protein measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Prostaglandin reductase 2 |
|---|---|
| UniProt accession | Q8N8N7 |
| Gene | PTGR2 |
| Organism | Homo sapiens |
| Length | 351 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (30)
Diseases linked to this target (Open Targets).
- neuroinflammatory disorder · score 0.27
- birth weight · score 0.22
- protein measurement · score 0.12
- head and neck squamous cell carcinoma · score 0.11
- platelet component distribution width · score 0.10
- mean corpuscular hemoglobin concentration · score 0.09
- mean corpuscular volume · score 0.08
- body height · score 0.06
- peak expiratory flow · score 0.04
- Red cell distribution width · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N8N7-F1 | alphafold | PREDICTED | 95.94 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N8N7.
Amino-acid sequence (351 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PTGR2?
The strongest Open Targets associations for PTGR2 are neuroinflammatory disorder, birth weight, protein measurement, head and neck squamous cell carcinoma and platelet component distribution width.
How long is the PTGR2 protein?
The Homo sapiens PTGR2 protein (UniProt Q8N8N7) is 351 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N8N7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N8N7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.