Probable transmembrane reductase CYB561D1 (CYB561D1)
Homo sapiens — UniProt Q8N8Q1
Data last refreshed: (UniProt release unknown)
Key facts
Probable transmembrane reductase CYB561D1 (CYB561D1) is a protein from Homo sapiens identified by UniProt accession Q8N8Q1, 229 residues long. MolForge cross-references it against 0 known binders and 22 disease associations.
- UniProt accession: Q8N8Q1; gene symbol CYB561D1.
- Organism: Homo sapiens.
- Length: 229 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, self reported educational attainment and intelligence.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Probable transmembrane reductase CYB561D1 |
|---|---|
| UniProt accession | Q8N8Q1 |
| Gene | CYB561D1 |
| Organism | Homo sapiens |
| Length | 229 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (22)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.31
- self reported educational attainment · score 0.21
- intelligence · score 0.17
- mathematical ability · score 0.16
- tobacco smoke exposure measurement · score 0.14
- schizophrenia · score 0.14
- sortilin measurement · score 0.13
- cognitive function measurement · score 0.11
- glomerular filtration rate · score 0.05
- chronotype measurement · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N8Q1-F1 | alphafold | PREDICTED | 88.50 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N8Q1.
Amino-acid sequence (229 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CYB561D1?
The strongest Open Targets associations for CYB561D1 are neurodegenerative disease, self reported educational attainment, intelligence, mathematical ability and tobacco smoke exposure measurement.
How long is the CYB561D1 protein?
The Homo sapiens CYB561D1 protein (UniProt Q8N8Q1) is 229 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N8Q1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N8Q1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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