Magnesium transporter NIPA2 (NIPA2)
Homo sapiens — UniProt Q8N8Q9
Data last refreshed: (UniProt release unknown)
Key facts
Magnesium transporter NIPA2 (NIPA2) is a protein from Homo sapiens identified by UniProt accession Q8N8Q9, 360 residues long. MolForge cross-references it against 0 known binders and 8 disease associations.
- UniProt accession: Q8N8Q9; gene symbol NIPA2.
- Organism: Homo sapiens.
- Length: 360 amino acids.
- Target class: Transporter.
- Top disease associations (Open Targets): heel bone mineral density, platelet component distribution width and bone quantitative ultrasound measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Magnesium transporter NIPA2 |
|---|---|
| UniProt accession | Q8N8Q9 |
| Gene | NIPA2 |
| Organism | Homo sapiens |
| Length | 360 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | Transporter (inferred from UniProt keywords / EC) |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (8)
Diseases linked to this target (Open Targets).
- heel bone mineral density · score 0.11
- platelet component distribution width · score 0.09
- bone quantitative ultrasound measurement · score 0.09
- type 2 diabetes mellitus · score 0.03
- visual perception measurement · score 0.03
- Osteoporosis · score 0.03
- multiple myeloma · score 0.01
- invasive breast ductal carcinoma · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N8Q9-F1 | alphafold | PREDICTED | 82.79 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N8Q9.
Amino-acid sequence (360 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with NIPA2?
The strongest Open Targets associations for NIPA2 are heel bone mineral density, platelet component distribution width, bone quantitative ultrasound measurement, type 2 diabetes mellitus and visual perception measurement.
How long is the NIPA2 protein?
The Homo sapiens NIPA2 protein (UniProt Q8N8Q9) is 360 amino acids long.
Browse: Targets: N · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N8Q9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N8Q9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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