Mitochondrial protein C2orf69 (C2orf69)
Homo sapiens — UniProt Q8N8R5
Data last refreshed: (UniProt release unknown)
Key facts
Mitochondrial protein C2orf69 (C2orf69) is a protein from Homo sapiens identified by UniProt accession Q8N8R5, 385 residues long. MolForge cross-references it against 0 known binders and 45 disease associations.
- UniProt accession: Q8N8R5; gene symbol C2orf69.
- Organism: Homo sapiens.
- Length: 385 amino acids.
- Top disease associations (Open Targets): combined oxidative phosphorylation deficiency, schizophrenia and Red cell distribution width.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Mitochondrial protein C2orf69 |
|---|---|
| UniProt accession | Q8N8R5 |
| Gene | C2orf69 |
| Organism | Homo sapiens |
| Length | 385 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (45)
Diseases linked to this target (Open Targets).
- combined oxidative phosphorylation deficiency · score 0.68
- schizophrenia · score 0.38
- Red cell distribution width · score 0.30
- smoking status measurement · score 0.28
- waist-hip ratio · score 0.26
- body weight · score 0.23
- bipolar disorder · score 0.23
- attention deficit hyperactivity disorder · score 0.23
- sleep duration · score 0.22
- anorexia nervosa · score 0.21
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N8R5-F1 | alphafold | PREDICTED | 77.88 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N8R5.
Amino-acid sequence (385 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with C2orf69?
The strongest Open Targets associations for C2orf69 are combined oxidative phosphorylation deficiency, schizophrenia, Red cell distribution width, smoking status measurement and waist-hip ratio.
How long is the C2orf69 protein?
The Homo sapiens C2orf69 protein (UniProt Q8N8R5) is 385 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N8R5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N8R5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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