ARL14 effector protein (ARL14EP)
Homo sapiens — UniProt Q8N8R7
Data last refreshed: (UniProt release unknown)
Key facts
ARL14 effector protein (ARL14EP) is a protein from Homo sapiens identified by UniProt accession Q8N8R7, 260 residues long. MolForge cross-references it against 0 known binders and 81 disease associations.
- UniProt accession: Q8N8R7; gene symbol ARL14EP.
- Organism: Homo sapiens.
- Length: 260 amino acids.
- Top disease associations (Open Targets): endometriosis, polycystic ovary syndrome and body mass index.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | ARL14 effector protein |
|---|---|
| UniProt accession | Q8N8R7 |
| Gene | ARL14EP |
| Organism | Homo sapiens |
| Length | 260 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (81)
Diseases linked to this target (Open Targets).
- endometriosis · score 0.45
- polycystic ovary syndrome · score 0.44
- body mass index · score 0.42
- heel bone mineral density · score 0.41
- systolic blood pressure · score 0.41
- Menorrhagia · score 0.40
- Ovarian cyst · score 0.38
- hormone measurement · score 0.37
- age at menarche · score 0.37
- body height · score 0.37
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N8R7-F1 | alphafold | PREDICTED | 80.67 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N8R7.
Amino-acid sequence (260 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ARL14EP?
The strongest Open Targets associations for ARL14EP are endometriosis, polycystic ovary syndrome, body mass index, heel bone mineral density and systolic blood pressure.
How long is the ARL14EP protein?
The Homo sapiens ARL14EP protein (UniProt Q8N8R7) is 260 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N8R7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N8R7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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