Protein enabled homolog (ENAH)
Homo sapiens — UniProt Q8N8S7
Data last refreshed: (UniProt release unknown)
Key facts
Protein enabled homolog (ENAH) is a protein from Homo sapiens identified by UniProt accession Q8N8S7, 591 residues long. MolForge cross-references it against 0 known binders and 193 disease associations.
- UniProt accession: Q8N8S7; gene symbol ENAH.
- Organism: Homo sapiens.
- Length: 591 amino acids.
- Top disease associations (Open Targets): serum gamma-glutamyl transferase measurement, neuroticism measurement and monocyte count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein enabled homolog |
|---|---|
| UniProt accession | Q8N8S7 |
| Gene | ENAH |
| Organism | Homo sapiens |
| Length | 591 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (193)
Diseases linked to this target (Open Targets).
- serum gamma-glutamyl transferase measurement · score 0.37
- neuroticism measurement · score 0.33
- monocyte count · score 0.26
- leukocyte count · score 0.26
- body mass index · score 0.24
- fat body mass · score 0.20
- breast adenocarcinoma · score 0.18
- electrocardiography · score 0.18
- myeloid white cell count · score 0.17
- worry measurement · score 0.16
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N8S7-F1 | alphafold | PREDICTED | 70.64 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N8S7.
Amino-acid sequence (591 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ENAH?
The strongest Open Targets associations for ENAH are serum gamma-glutamyl transferase measurement, neuroticism measurement, monocyte count, leukocyte count and body mass index.
How long is the ENAH protein?
The Homo sapiens ENAH protein (UniProt Q8N8S7) is 591 amino acids long.
Browse: Targets: E · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N8S7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N8S7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.