Chromodomain Y-like protein 2 (CDYL2)
Homo sapiens — UniProt Q8N8U2
Data last refreshed: (UniProt release unknown)
Key facts
Chromodomain Y-like protein 2 (CDYL2) is a protein from Homo sapiens identified by UniProt accession Q8N8U2, 506 residues long. MolForge cross-references it against 0 known binders and 61 disease associations.
- UniProt accession: Q8N8U2; gene symbol CDYL2.
- Organism: Homo sapiens.
- Length: 506 amino acids.
- Top disease associations (Open Targets): alkaline phosphatase measurement, heel bone mineral density and systolic blood pressure.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Chromodomain Y-like protein 2 |
|---|---|
| UniProt accession | Q8N8U2 |
| Gene | CDYL2 |
| Organism | Homo sapiens |
| Length | 506 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (61)
Diseases linked to this target (Open Targets).
- alkaline phosphatase measurement · score 0.46
- heel bone mineral density · score 0.46
- systolic blood pressure · score 0.36
- pulse pressure measurement · score 0.36
- balding measurement · score 0.36
- lymphocyte count · score 0.33
- physical activity measurement · score 0.33
- inflammatory bowel disease · score 0.33
- hair shape measurement · score 0.32
- Immature Reticulocyte Fraction Measurement · score 0.32
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N8U2-F1 | alphafold | PREDICTED | 71.58 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N8U2.
Amino-acid sequence (506 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CDYL2?
The strongest Open Targets associations for CDYL2 are alkaline phosphatase measurement, heel bone mineral density, systolic blood pressure, pulse pressure measurement and balding measurement.
How long is the CDYL2 protein?
The Homo sapiens CDYL2 protein (UniProt Q8N8U2) is 506 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N8U2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N8U2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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