Protein mab-21-like 3 (MAB21L3)
Homo sapiens — UniProt Q8N8X9
Data last refreshed: (UniProt release unknown)
Key facts
Protein mab-21-like 3 (MAB21L3) is a protein from Homo sapiens identified by UniProt accession Q8N8X9, 362 residues long. MolForge cross-references it against 0 known binders and 50 disease associations.
- UniProt accession: Q8N8X9; gene symbol MAB21L3.
- Organism: Homo sapiens.
- Length: 362 amino acids.
- Top disease associations (Open Targets): granulocyte count, macula measurement and calcium measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein mab-21-like 3 |
|---|---|
| UniProt accession | Q8N8X9 |
| Gene | MAB21L3 |
| Organism | Homo sapiens |
| Length | 362 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (50)
Diseases linked to this target (Open Targets).
- granulocyte count · score 0.27
- macula measurement · score 0.25
- calcium measurement · score 0.08
- blood protein measurement · score 0.06
- esophageal adenocarcinoma · score 0.03
- breast carcinoma · score 0.02
- esophageal squamous cell carcinoma · score 0.02
- oral squamous cell carcinoma · score 0.01
- chronic interstitial cystitis · score 0.01
- neoplasm · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N8X9-F1 | alphafold | PREDICTED | 90.38 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N8X9.
Amino-acid sequence (362 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MAB21L3?
The strongest Open Targets associations for MAB21L3 are granulocyte count, macula measurement, calcium measurement, blood protein measurement and esophageal adenocarcinoma.
How long is the MAB21L3 protein?
The Homo sapiens MAB21L3 protein (UniProt Q8N8X9) is 362 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N8X9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N8X9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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