V-type proton ATPase subunit d 2 (ATP6V0D2)
Homo sapiens — UniProt Q8N8Y2
Data last refreshed: (UniProt release unknown)
Key facts
V-type proton ATPase subunit d 2 (ATP6V0D2) is a protein from Homo sapiens identified by UniProt accession Q8N8Y2, 350 residues long. MolForge cross-references it against 0 known binders and 66 disease associations.
- UniProt accession: Q8N8Y2; gene symbol ATP6V0D2.
- Organism: Homo sapiens.
- Length: 350 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, leukocyte count and total cholesterol measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | V-type proton ATPase subunit d 2 |
|---|---|
| UniProt accession | Q8N8Y2 |
| Gene | ATP6V0D2 |
| Organism | Homo sapiens |
| Length | 350 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (66)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.37
- leukocyte count · score 0.29
- total cholesterol measurement · score 0.28
- neutrophil count · score 0.26
- adolescent idiopathic scoliosis · score 0.23
- breast adenocarcinoma · score 0.21
- myeloid white cell count · score 0.18
- total blood protein measurement · score 0.16
- glioblastoma multiforme · score 0.14
- self reported educational attainment · score 0.11
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N8Y2-F1 | alphafold | PREDICTED | 85.42 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N8Y2.
Amino-acid sequence (350 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ATP6V0D2?
The strongest Open Targets associations for ATP6V0D2 are neurodegenerative disease, leukocyte count, total cholesterol measurement, neutrophil count and adolescent idiopathic scoliosis.
How long is the ATP6V0D2 protein?
The Homo sapiens ATP6V0D2 protein (UniProt Q8N8Y2) is 350 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N8Y2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N8Y2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.