Zinc finger protein 41 homolog (ZFP41)
Homo sapiens — UniProt Q8N8Y5
Data last refreshed: (UniProt release unknown)
Key facts
Zinc finger protein 41 homolog (ZFP41) is a protein from Homo sapiens identified by UniProt accession Q8N8Y5, 198 residues long. MolForge cross-references it against 0 known binders and 14 disease associations.
- UniProt accession: Q8N8Y5; gene symbol ZFP41.
- Organism: Homo sapiens.
- Length: 198 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, appendicular lean mass and body height.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc finger protein 41 homolog |
|---|---|
| UniProt accession | Q8N8Y5 |
| Gene | ZFP41 |
| Organism | Homo sapiens |
| Length | 198 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (14)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.33
- appendicular lean mass · score 0.22
- body height · score 0.14
- erythrocyte count · score 0.11
- mean corpuscular hemoglobin · score 0.08
- hepatocellular carcinoma · score 0.06
- BMI-adjusted hip circumference · score 0.06
- mean corpuscular volume · score 0.05
- mean reticulocyte volume · score 0.04
- cortical thickness · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N8Y5-F1 | alphafold | PREDICTED | 69.60 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N8Y5.
Amino-acid sequence (198 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZFP41?
The strongest Open Targets associations for ZFP41 are neurodegenerative disease, appendicular lean mass, body height, erythrocyte count and mean corpuscular hemoglobin.
How long is the ZFP41 protein?
The Homo sapiens ZFP41 protein (UniProt Q8N8Y5) is 198 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N8Y5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N8Y5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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