Discoidin, CUB and LCCL domain-containing protein 1 (DCBLD1)
Homo sapiens — UniProt Q8N8Z6
Data last refreshed: (UniProt release unknown)
Key facts
Discoidin, CUB and LCCL domain-containing protein 1 (DCBLD1) is a protein from Homo sapiens identified by UniProt accession Q8N8Z6, 715 residues long. MolForge cross-references it against 0 known binders and 54 disease associations.
- UniProt accession: Q8N8Z6; gene symbol DCBLD1.
- Organism: Homo sapiens.
- Length: 715 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, body height and lung carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Discoidin, CUB and LCCL domain-containing protein 1 |
|---|---|
| UniProt accession | Q8N8Z6 |
| Gene | DCBLD1 |
| Organism | Homo sapiens |
| Length | 715 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (54)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.45
- body height · score 0.39
- lung carcinoma · score 0.37
- type 2 diabetes mellitus · score 0.36
- FEV/FVC ratio · score 0.36
- systolic blood pressure · score 0.35
- skin cancer · score 0.30
- diastolic blood pressure · score 0.29
- hemorrhoid · score 0.28
- BMI-adjusted waist circumference · score 0.21
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N8Z6-F1 | alphafold | PREDICTED | 67.56 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N8Z6.
Amino-acid sequence (715 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with DCBLD1?
The strongest Open Targets associations for DCBLD1 are neurodegenerative disease, body height, lung carcinoma, type 2 diabetes mellitus and FEV/FVC ratio.
How long is the DCBLD1 protein?
The Homo sapiens DCBLD1 protein (UniProt Q8N8Z6) is 715 amino acids long.
Browse: Targets: D · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N8Z6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N8Z6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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