Zinc finger protein 441 (ZNF441)
Homo sapiens — UniProt Q8N8Z8
Data last refreshed: (UniProt release unknown)
Key facts
Zinc finger protein 441 (ZNF441) is a protein from Homo sapiens identified by UniProt accession Q8N8Z8, 693 residues long. MolForge cross-references it against 0 known binders and 8 disease associations.
- UniProt accession: Q8N8Z8; gene symbol ZNF441.
- Organism: Homo sapiens.
- Length: 693 amino acids.
- Top disease associations (Open Targets): blood phosphate measurement, neutrophil count and leukocyte count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc finger protein 441 |
|---|---|
| UniProt accession | Q8N8Z8 |
| Gene | ZNF441 |
| Organism | Homo sapiens |
| Length | 693 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (8)
Diseases linked to this target (Open Targets).
- blood phosphate measurement · score 0.12
- neutrophil count · score 0.09
- leukocyte count · score 0.09
- myeloid white cell count · score 0.08
- Down syndrome · score 0.03
- 3-hydroxypropylmercapturic acid measurement · score 0.03
- X-linked hyper-IgM syndrome · score 0.00
- neoplasm · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N8Z8-F1 | alphafold | PREDICTED | 69.60 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N8Z8.
Amino-acid sequence (693 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZNF441?
The strongest Open Targets associations for ZNF441 are blood phosphate measurement, neutrophil count, leukocyte count, myeloid white cell count and Down syndrome.
How long is the ZNF441 protein?
The Homo sapiens ZNF441 protein (UniProt Q8N8Z8) is 693 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N8Z8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N8Z8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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