Nuclear envelope phosphatase-regulatory subunit 1 (CNEP1R1)
Homo sapiens — UniProt Q8N9A8
Data last refreshed: (UniProt release unknown)
Key facts
Nuclear envelope phosphatase-regulatory subunit 1 (CNEP1R1) is a protein from Homo sapiens identified by UniProt accession Q8N9A8, 125 residues long. MolForge cross-references it against 0 known binders and 45 disease associations.
- UniProt accession: Q8N9A8; gene symbol CNEP1R1.
- Organism: Homo sapiens.
- Length: 125 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, appendicular lean mass and lysosomal storage disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Nuclear envelope phosphatase-regulatory subunit 1 |
|---|---|
| UniProt accession | Q8N9A8 |
| Gene | CNEP1R1 |
| Organism | Homo sapiens |
| Length | 125 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (45)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.52
- appendicular lean mass · score 0.31
- lysosomal storage disease · score 0.29
- gut microbiome measurement · score 0.29
- epilepsy · score 0.26
- mean corpuscular hemoglobin · score 0.23
- mean corpuscular volume · score 0.19
- mosaic loss of chromosome Y measurement · score 0.18
- Red cell distribution width · score 0.18
- myeloid white cell count · score 0.14
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N9A8-F1 | alphafold | PREDICTED | 90.29 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N9A8.
Amino-acid sequence (125 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CNEP1R1?
The strongest Open Targets associations for CNEP1R1 are neurodegenerative disease, appendicular lean mass, lysosomal storage disease, gut microbiome measurement and epilepsy.
How long is the CNEP1R1 protein?
The Homo sapiens CNEP1R1 protein (UniProt Q8N9A8) is 125 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N9A8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N9A8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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