Immunoglobulin superfamily member 22 (IGSF22)
Homo sapiens — UniProt Q8N9C0
Data last refreshed: (UniProt release unknown)
Key facts
Immunoglobulin superfamily member 22 (IGSF22) is a protein from Homo sapiens identified by UniProt accession Q8N9C0, 903 residues long. MolForge cross-references it against 0 known binders and 10 disease associations.
- UniProt accession: Q8N9C0; gene symbol IGSF22.
- Organism: Homo sapiens.
- Length: 903 amino acids.
- Top disease associations (Open Targets): alcohol dependence, risky sexual behaviour measurement and Abnormality of refraction.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Immunoglobulin superfamily member 22 |
|---|---|
| UniProt accession | Q8N9C0 |
| Gene | IGSF22 |
| Organism | Homo sapiens |
| Length | 903 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (10)
Diseases linked to this target (Open Targets).
- alcohol dependence · score 0.32
- risky sexual behaviour measurement · score 0.32
- Abnormality of refraction · score 0.08
- Myopia · score 0.07
- refractive error · score 0.07
- chronic kidney disease · score 0.01
- breast cancer · score 0.00
- esophageal squamous cell carcinoma · score 0.00
- renal carcinoma · score 0.00
- psoriasis · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N9C0-F1 | alphafold | PREDICTED | 85.36 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N9C0.
Amino-acid sequence (903 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with IGSF22?
The strongest Open Targets associations for IGSF22 are alcohol dependence, risky sexual behaviour measurement, Abnormality of refraction, Myopia and refractive error.
How long is the IGSF22 protein?
The Homo sapiens IGSF22 protein (UniProt Q8N9C0) is 903 amino acids long.
Browse: Targets: I · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N9C0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N9C0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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