Transmembrane protein 102 (TMEM102)
Homo sapiens — UniProt Q8N9M5
Data last refreshed: (UniProt release unknown)
Key facts
Transmembrane protein 102 (TMEM102) is a protein from Homo sapiens identified by UniProt accession Q8N9M5, 508 residues long. MolForge cross-references it against 0 known binders and 26 disease associations.
- UniProt accession: Q8N9M5; gene symbol TMEM102.
- Organism: Homo sapiens.
- Length: 508 amino acids.
- Top disease associations (Open Targets): sex hormone-binding globulin measurement, cancer and testosterone measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Transmembrane protein 102 |
|---|---|
| UniProt accession | Q8N9M5 |
| Gene | TMEM102 |
| Organism | Homo sapiens |
| Length | 508 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (26)
Diseases linked to this target (Open Targets).
- sex hormone-binding globulin measurement · score 0.54
- cancer · score 0.11
- testosterone measurement · score 0.06
- balding measurement · score 0.05
- puberty onset measurement · score 0.05
- red blood cell density measurement · score 0.05
- serum gamma-glutamyl transferase measurement · score 0.04
- erythrocyte count · score 0.04
- acute lymphoblastic leukemia · score 0.03
- IGF-1 measurement · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N9M5-F1 | alphafold | PREDICTED | 74.66 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N9M5.
Amino-acid sequence (508 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TMEM102?
The strongest Open Targets associations for TMEM102 are sex hormone-binding globulin measurement, cancer, testosterone measurement, balding measurement and puberty onset measurement.
How long is the TMEM102 protein?
The Homo sapiens TMEM102 protein (UniProt Q8N9M5) is 508 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N9M5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N9M5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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