Leucine-rich repeat-containing protein 57 (LRRC57)
Homo sapiens — UniProt Q8N9N7
Data last refreshed: (UniProt release unknown)
Key facts
Leucine-rich repeat-containing protein 57 (LRRC57) is a protein from Homo sapiens identified by UniProt accession Q8N9N7, 239 residues long. MolForge cross-references it against 0 known binders and 12 disease associations.
- UniProt accession: Q8N9N7; gene symbol LRRC57.
- Organism: Homo sapiens.
- Length: 239 amino acids.
- Top disease associations (Open Targets): mean corpuscular volume, bipolar disorder and erythrocyte count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Leucine-rich repeat-containing protein 57 |
|---|---|
| UniProt accession | Q8N9N7 |
| Gene | LRRC57 |
| Organism | Homo sapiens |
| Length | 239 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (12)
Diseases linked to this target (Open Targets).
- mean corpuscular volume · score 0.07
- bipolar disorder · score 0.04
- erythrocyte count · score 0.04
- hemoglobin measurement · score 0.03
- sex hormone-binding globulin measurement · score 0.03
- bipolar I disorder · score 0.03
- unipolar depression · score 0.03
- blood protein measurement · score 0.02
- type 1 diabetes mellitus · score 0.00
- neurotic disorder · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N9N7-F1 | alphafold | PREDICTED | 95.73 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N9N7.
Amino-acid sequence (239 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with LRRC57?
The strongest Open Targets associations for LRRC57 are mean corpuscular volume, bipolar disorder, erythrocyte count, hemoglobin measurement and sex hormone-binding globulin measurement.
How long is the LRRC57 protein?
The Homo sapiens LRRC57 protein (UniProt Q8N9N7) is 239 amino acids long.
Browse: Targets: L · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N9N7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N9N7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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