Protein SREK1IP1 (SREK1IP1)
Homo sapiens — UniProt Q8N9Q2
Data last refreshed: (UniProt release unknown)
Key facts
Protein SREK1IP1 (SREK1IP1) is a protein from Homo sapiens identified by UniProt accession Q8N9Q2, 155 residues long. MolForge cross-references it against 0 known binders and 42 disease associations.
- UniProt accession: Q8N9Q2; gene symbol SREK1IP1.
- Organism: Homo sapiens.
- Length: 155 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, cognitive function measurement and intelligence.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein SREK1IP1 |
|---|---|
| UniProt accession | Q8N9Q2 |
| Gene | SREK1IP1 |
| Organism | Homo sapiens |
| Length | 155 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (42)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.35
- cognitive function measurement · score 0.32
- intelligence · score 0.28
- self reported educational attainment · score 0.23
- verbal-numerical reasoning measurement · score 0.23
- age at menarche · score 0.23
- insulin like growth factor measurement · score 0.23
- body mass index · score 0.11
- refractive error measurement · score 0.10
- protein measurement · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N9Q2-F1 | alphafold | PREDICTED | 63.68 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N9Q2.
Amino-acid sequence (155 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SREK1IP1?
The strongest Open Targets associations for SREK1IP1 are neurodegenerative disease, cognitive function measurement, intelligence, self reported educational attainment and verbal-numerical reasoning measurement.
How long is the SREK1IP1 protein?
The Homo sapiens SREK1IP1 protein (UniProt Q8N9Q2) is 155 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N9Q2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N9Q2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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