CMT1A duplicated region transcript 4 protein (CDRT4)
Homo sapiens — UniProt Q8N9R6
Data last refreshed: (UniProt release unknown)
Key facts
CMT1A duplicated region transcript 4 protein (CDRT4) is a protein from Homo sapiens identified by UniProt accession Q8N9R6, 152 residues long. MolForge cross-references it against 0 known binders and 7 disease associations.
- UniProt accession: Q8N9R6; gene symbol CDRT4.
- Organism: Homo sapiens.
- Length: 152 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, resting heart rate and diastolic blood pressure.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | CMT1A duplicated region transcript 4 protein |
|---|---|
| UniProt accession | Q8N9R6 |
| Gene | CDRT4 |
| Organism | Homo sapiens |
| Length | 152 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (7)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.22
- resting heart rate · score 0.17
- diastolic blood pressure · score 0.16
- diet measurement · score 0.06
- acute myocardial infarction · score 0.01
- idiopathic pulmonary fibrosis · score 0.00
- axial length measurement · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N9R6-F1 | alphafold | PREDICTED | 65.90 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N9R6.
Amino-acid sequence (152 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CDRT4?
The strongest Open Targets associations for CDRT4 are neurodegenerative disease, resting heart rate, diastolic blood pressure, diet measurement and acute myocardial infarction.
How long is the CDRT4 protein?
The Homo sapiens CDRT4 protein (UniProt Q8N9R6) is 152 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N9R6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N9R6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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