Protein SCAI (SCAI)
Homo sapiens — UniProt Q8N9R8
Data last refreshed: (UniProt release unknown)
Key facts
Protein SCAI (SCAI) is a protein from Homo sapiens identified by UniProt accession Q8N9R8, 606 residues long. MolForge cross-references it against 0 known binders and 115 disease associations.
- UniProt accession: Q8N9R8; gene symbol SCAI.
- Organism: Homo sapiens.
- Length: 606 amino acids.
- Top disease associations (Open Targets): smoking cessation, substance abuse and attention deficit hyperactivity disorder.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein SCAI |
|---|---|
| UniProt accession | Q8N9R8 |
| Gene | SCAI |
| Organism | Homo sapiens |
| Length | 606 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (115)
Diseases linked to this target (Open Targets).
- smoking cessation · score 0.39
- substance abuse · score 0.29
- attention deficit hyperactivity disorder · score 0.29
- antisocial behaviour measurement · score 0.29
- pulse pressure measurement · score 0.27
- neurodegenerative disease · score 0.26
- neuroticism measurement · score 0.25
- systolic blood pressure · score 0.24
- smoking behavior · score 0.20
- peak expiratory flow · score 0.20
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N9R8-F1 | alphafold | PREDICTED | 85.64 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N9R8.
Amino-acid sequence (606 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SCAI?
The strongest Open Targets associations for SCAI are smoking cessation, substance abuse, attention deficit hyperactivity disorder, antisocial behaviour measurement and pulse pressure measurement.
How long is the SCAI protein?
The Homo sapiens SCAI protein (UniProt Q8N9R8) is 606 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N9R8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N9R8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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