Sorting nexin-31 (SNX31)
Homo sapiens — UniProt Q8N9S9
Data last refreshed: (UniProt release unknown)
Key facts
Sorting nexin-31 (SNX31) is a protein from Homo sapiens identified by UniProt accession Q8N9S9, 440 residues long. MolForge cross-references it against 0 known binders and 47 disease associations.
- UniProt accession: Q8N9S9; gene symbol SNX31.
- Organism: Homo sapiens.
- Length: 440 amino acids.
- Top disease associations (Open Targets): systolic blood pressure, neuroimaging measurement and cortical thickness.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Sorting nexin-31 |
|---|---|
| UniProt accession | Q8N9S9 |
| Gene | SNX31 |
| Organism | Homo sapiens |
| Length | 440 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (47)
Diseases linked to this target (Open Targets).
- systolic blood pressure · score 0.41
- neuroimaging measurement · score 0.40
- cortical thickness · score 0.39
- diastolic blood pressure · score 0.37
- brain volume measurement · score 0.35
- IGF-1 measurement · score 0.29
- hypertension · score 0.28
- brain measurement · score 0.28
- mean arterial pressure · score 0.28
- insulin like growth factor measurement · score 0.28
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N9S9-F1 | alphafold | PREDICTED | 84.66 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N9S9.
Amino-acid sequence (440 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SNX31?
The strongest Open Targets associations for SNX31 are systolic blood pressure, neuroimaging measurement, cortical thickness, diastolic blood pressure and brain volume measurement.
How long is the SNX31 protein?
The Homo sapiens SNX31 protein (UniProt Q8N9S9) is 440 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N9S9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N9S9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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