Protein KRI1 homolog (KRI1)
Homo sapiens — UniProt Q8N9T8
Data last refreshed: (UniProt release unknown)
Key facts
Protein KRI1 homolog (KRI1) is a protein from Homo sapiens identified by UniProt accession Q8N9T8, 703 residues long. MolForge cross-references it against 0 known binders and 45 disease associations.
- UniProt accession: Q8N9T8; gene symbol KRI1.
- Organism: Homo sapiens.
- Length: 703 amino acids.
- Top disease associations (Open Targets): neutrophil count, leukocyte count and monocyte percentage of leukocytes.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein KRI1 homolog |
|---|---|
| UniProt accession | Q8N9T8 |
| Gene | KRI1 |
| Organism | Homo sapiens |
| Length | 703 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (45)
Diseases linked to this target (Open Targets).
- neutrophil count · score 0.31
- leukocyte count · score 0.29
- monocyte percentage of leukocytes · score 0.22
- neurodegenerative disease · score 0.22
- myeloid white cell count · score 0.21
- Red cell distribution width · score 0.14
- neutrophil percentage of leukocytes · score 0.13
- platelet count · score 0.12
- mean corpuscular volume · score 0.10
- platelet crit · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N9T8-F1 | alphafold | PREDICTED | 69.44 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N9T8.
Amino-acid sequence (703 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with KRI1?
The strongest Open Targets associations for KRI1 are neutrophil count, leukocyte count, monocyte percentage of leukocytes, neurodegenerative disease and myeloid white cell count.
How long is the KRI1 protein?
The Homo sapiens KRI1 protein (UniProt Q8N9T8) is 703 amino acids long.
Browse: Targets: K · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N9T8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N9T8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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