Tandem C2 domains nuclear protein (TC2N)
Homo sapiens — UniProt Q8N9U0
Data last refreshed: (UniProt release unknown)
Key facts
Tandem C2 domains nuclear protein (TC2N) is a protein from Homo sapiens identified by UniProt accession Q8N9U0, 490 residues long. MolForge cross-references it against 0 known binders and 64 disease associations.
- UniProt accession: Q8N9U0; gene symbol TC2N.
- Organism: Homo sapiens.
- Length: 490 amino acids.
- Top disease associations (Open Targets): body height, calcium measurement and platelet count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Tandem C2 domains nuclear protein |
|---|---|
| UniProt accession | Q8N9U0 |
| Gene | TC2N |
| Organism | Homo sapiens |
| Length | 490 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (64)
Diseases linked to this target (Open Targets).
- body height · score 0.45
- calcium measurement · score 0.45
- platelet count · score 0.40
- mean platelet volume · score 0.39
- von Willebrand factor measurement · score 0.38
- sitting height measurement · score 0.31
- coagulation factor measurement · score 0.27
- blood phosphate measurement · score 0.27
- appendicular lean mass · score 0.26
- platelet component distribution width · score 0.25
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N9U0-F1 | alphafold | PREDICTED | 67.63 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N9U0.
Amino-acid sequence (490 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TC2N?
The strongest Open Targets associations for TC2N are body height, calcium measurement, platelet count, mean platelet volume and von Willebrand factor measurement.
How long is the TC2N protein?
The Homo sapiens TC2N protein (UniProt Q8N9U0) is 490 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N9U0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N9U0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.