WD repeat, SAM and U-box domain-containing protein 1 (WDSUB1)
Homo sapiens — UniProt Q8N9V3
Data last refreshed: (UniProt release unknown)
Key facts
WD repeat, SAM and U-box domain-containing protein 1 (WDSUB1) is a protein from Homo sapiens identified by UniProt accession Q8N9V3, 476 residues long. MolForge cross-references it against 0 known binders and 32 disease associations.
- UniProt accession: Q8N9V3; gene symbol WDSUB1.
- Organism: Homo sapiens.
- Length: 476 amino acids.
- Top disease associations (Open Targets): Red cell distribution width, reticulocyte count and neurodegenerative disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | WD repeat, SAM and U-box domain-containing protein 1 |
|---|---|
| UniProt accession | Q8N9V3 |
| Gene | WDSUB1 |
| Organism | Homo sapiens |
| Length | 476 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (32)
Diseases linked to this target (Open Targets).
- Red cell distribution width · score 0.40
- reticulocyte count · score 0.38
- neurodegenerative disease · score 0.37
- mean corpuscular volume · score 0.35
- reticulocyte measurement · score 0.32
- ferritin measurement · score 0.27
- sudden cardiac arrest · score 0.25
- neuroinflammatory disorder · score 0.19
- bone quantitative ultrasound measurement · score 0.17
- heel bone mineral density · score 0.17
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N9V3-F1 | alphafold | PREDICTED | 88.88 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N9V3.
Amino-acid sequence (476 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with WDSUB1?
The strongest Open Targets associations for WDSUB1 are Red cell distribution width, reticulocyte count, neurodegenerative disease, mean corpuscular volume and reticulocyte measurement.
How long is the WDSUB1 protein?
The Homo sapiens WDSUB1 protein (UniProt Q8N9V3) is 476 amino acids long.
Browse: Targets: W · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N9V3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N9V3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.