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Protein boule-like (BOLL)

Homo sapiens — UniProt Q8N9W6

Gene: BOLLHomo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Protein boule-like (BOLL) is a protein from Homo sapiens identified by UniProt accession Q8N9W6, 283 residues long. MolForge cross-references it against 0 known binders and 162 disease associations.

  • UniProt accession: Q8N9W6; gene symbol BOLL.
  • Organism: Homo sapiens.
  • Length: 283 amino acids.
  • Top disease associations (Open Targets): body mass index, appendicular lean mass and lean body mass.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameProtein boule-like
UniProt accessionQ8N9W6
GeneBOLL
OrganismHomo sapiens
Length283 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (162)

Diseases linked to this target (Open Targets).

  • body mass index · score 0.23
  • appendicular lean mass · score 0.23
  • lean body mass · score 0.22
  • monocyte count · score 0.22
  • fat body mass · score 0.21
  • leukocyte count · score 0.19
  • BMI-adjusted waist circumference · score 0.13
  • atopic asthma · score 0.13
  • genetic disorder · score 0.12
  • red blood cell density measurement · score 0.12

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q8N9W6-F1alphafoldPREDICTED63.82—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N9W6.

Amino-acid sequence (283 residues)

MQTDSLSPSP NPVSPVPLNN PTSAPRYGTV IPNRIFVGGI DFKTNESDLR KFFSQYGSVK EVKIVNDRAG VSKGYGFVTF ETQEDAQKIL QEAEKLNYKD KKLNIGPAIR KQQVGIPRSS IMPAAGTMYL TTSTGYPYTY HNGVAYFHTP EVTSVPPPWP SRSVCSSPVM VAQPIYQQPA YHYQATTQYL PGQWQWSVPQ PSASSAPFLY LQPSEVIYQP VEIAQDGGCV PPPLSLMETS VPEPYSDHGV QATYHQVYAP SAITMPAPVM QPEPIKTVWS IHY

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with BOLL?

The strongest Open Targets associations for BOLL are body mass index, appendicular lean mass, lean body mass, monocyte count and fat body mass.

How long is the BOLL protein?

The Homo sapiens BOLL protein (UniProt Q8N9W6) is 283 amino acids long.

Browse: Targets: B · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ8N9W6
GeneBOLL
OrganismHomo sapiens
Length283
Binders0
Diseases162
View on UniProt