Protein FAM181A (FAM181A)
Homo sapiens — UniProt Q8N9Y4
Data last refreshed: (UniProt release unknown)
Key facts
Protein FAM181A (FAM181A) is a protein from Homo sapiens identified by UniProt accession Q8N9Y4, 354 residues long. MolForge cross-references it against 0 known binders and 24 disease associations.
- UniProt accession: Q8N9Y4; gene symbol FAM181A.
- Organism: Homo sapiens.
- Length: 354 amino acids.
- Top disease associations (Open Targets): FEV/FVC ratio, monocyte count and metabolite measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein FAM181A |
|---|---|
| UniProt accession | Q8N9Y4 |
| Gene | FAM181A |
| Organism | Homo sapiens |
| Length | 354 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (24)
Diseases linked to this target (Open Targets).
- FEV/FVC ratio · score 0.29
- monocyte count · score 0.17
- metabolite measurement · score 0.12
- lung adenocarcinoma · score 0.07
- eosinophil count · score 0.06
- vital capacity · score 0.06
- Down syndrome · score 0.04
- eosinophil percentage of leukocytes · score 0.03
- self reported educational attainment · score 0.03
- lifestyle measurement · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N9Y4-F1 | alphafold | PREDICTED | 59.32 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N9Y4.
Amino-acid sequence (354 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with FAM181A?
The strongest Open Targets associations for FAM181A are FEV/FVC ratio, monocyte count, metabolite measurement, lung adenocarcinoma and eosinophil count.
How long is the FAM181A protein?
The Homo sapiens FAM181A protein (UniProt Q8N9Y4) is 354 amino acids long.
Browse: Targets: F · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N9Y4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N9Y4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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