Lamin tail domain-containing protein 1 (LMNTD1)
Homo sapiens — UniProt Q8N9Z9
Data last refreshed: (UniProt release unknown)
Key facts
Lamin tail domain-containing protein 1 (LMNTD1) is a protein from Homo sapiens identified by UniProt accession Q8N9Z9, 388 residues long. MolForge cross-references it against 0 known binders and 11 disease associations.
- UniProt accession: Q8N9Z9; gene symbol LMNTD1.
- Organism: Homo sapiens.
- Length: 388 amino acids.
- Top disease associations (Open Targets): bone disease, diffuse plaque measurement and sphingomyelin measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Lamin tail domain-containing protein 1 |
|---|---|
| UniProt accession | Q8N9Z9 |
| Gene | LMNTD1 |
| Organism | Homo sapiens |
| Length | 388 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (11)
Diseases linked to this target (Open Targets).
- bone disease · score 0.16
- diffuse plaque measurement · score 0.12
- sphingomyelin measurement · score 0.05
- heel bone mineral density · score 0.05
- metabolite measurement · score 0.04
- COVID-19 · score 0.01
- lung adenoma · score 0.01
- uterine leiomyosarcoma · score 0.00
- endometrial carcinoma · score 0.00
- cancer · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N9Z9-F1 | alphafold | PREDICTED | 56.82 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N9Z9.
Amino-acid sequence (388 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with LMNTD1?
The strongest Open Targets associations for LMNTD1 are bone disease, diffuse plaque measurement, sphingomyelin measurement, heel bone mineral density and metabolite measurement.
How long is the LMNTD1 protein?
The Homo sapiens LMNTD1 protein (UniProt Q8N9Z9) is 388 amino acids long.
Browse: Targets: L · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N9Z9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N9Z9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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