About Centrosomal protein POC5
Centrosomal protein POC5 (POC5) is a protein
from Homo sapiens identified by UniProt accession
Q8NA72, 575 residues long.
MolForge cross-references it against 0 known binders and
63 disease associations.
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
Disease associations (63)
Diseases linked to this target (Open Targets).
- body mass index · score 0.39
- diastolic blood pressure · score 0.37
- lean body mass · score 0.36
- fat body mass · score 0.34
- syndromic retinitis pigmentosa · score 0.33
- body weight · score 0.33
- high density lipoprotein cholesterol measurement · score 0.33
- body fat percentage · score 0.32
- type 2 diabetes mellitus · score 0.31
- snoring measurement · score 0.31
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
Experimental structures are not indexed in MolForge yet —
search RCSB PDB for Q8NA72.
Amino-acid sequence (575 residues)
MSSDEEKYSL PVVQNDSSRG SSVSSNLQEE YEELLHYAIV TPNIEPCASQ SSHPKGELVP DVRISTIHDI LHSQGNNSEV RETAIEVGKG CDFHISSHSK TDESSPVLSP RKPSHPVMDF FSSHLLADSS SPATNSSHTD AHEILVSDFL VSDENLQKME NVLDLWSSGL KTNIISELSK WRLNFIDWHR MEMRKEKEKH AAHLKQLCNQ INELKELQKT FEISIGRKDE VISSLSHAIG KQKEKIELMR TFFHWRIGHV RARQDVYEGK LADQYYQRTL LKKVWKVWRS VVQKQWKDVV ERACQARAEE VCIQISNDYE AKVAMLSGAL ENAKAEIQRM QHEKEHFEDS MKKAFMRGVC ALNLEAMTIF QNRNDAGIDS TNNKKEEYGP GVQGKEHSAH LDPSAPPMPL PVTSPLLPSP PAAVGGASAT AVPSAASMTS TRAASASSVH VPVSALGAGS AATAASEEMY VPRVVTSAQQ KAGRTITARI TGRCDFASKN RISSSLAIMG VSPPMSSVVV EKHHPVTVQT IPQATAAKYP RTIHPESSTS ASRSLGTRSA HTQSLTSVHS IKVVD
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