Draxin (DRAXIN)
Homo sapiens — UniProt Q8NBI3
Data last refreshed: (UniProt release unknown)
Key facts
Draxin (DRAXIN) is a protein from Homo sapiens identified by UniProt accession Q8NBI3, 349 residues long. MolForge cross-references it against 0 known binders and 80 disease associations.
- UniProt accession: Q8NBI3; gene symbol DRAXIN.
- Organism: Homo sapiens.
- Length: 349 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, schizencephaly and mirror movements 1.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Draxin |
|---|---|
| UniProt accession | Q8NBI3 |
| Gene | DRAXIN |
| Organism | Homo sapiens |
| Length | 349 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (80)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.36
- schizencephaly · score 0.09
- mirror movements 1 · score 0.07
- Polymicrogyria due to TUBB2B mutation · score 0.06
- Cortical dysgenesis with pontocerebellar hypoplasia due to TUBB3 mutation · score 0.06
- microcephaly-polymicrogyria-corpus callosum agenesis syndrome · score 0.05
- Genetic central nervous system malformation · score 0.05
- hyperinsulinism due to INSR deficiency · score 0.05
- polymicrogyria with optic nerve hypoplasia · score 0.05
- autosomal recessive primary microcephaly · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8NBI3-F1 | alphafold | PREDICTED | 58.46 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8NBI3.
Amino-acid sequence (349 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with DRAXIN?
The strongest Open Targets associations for DRAXIN are neurodegenerative disease, schizencephaly, mirror movements 1, Polymicrogyria due to TUBB2B mutation and Cortical dysgenesis with pontocerebellar hypoplasia due to TUBB3 mutation.
How long is the DRAXIN protein?
The Homo sapiens DRAXIN protein (UniProt Q8NBI3) is 349 amino acids long.
Browse: Targets: D · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8NBI3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8NBI3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.