Xyloside xylosyltransferase 1 (XXYLT1)
Homo sapiens — UniProt Q8NBI6
Data last refreshed: (UniProt release unknown)
Key facts
Xyloside xylosyltransferase 1 (XXYLT1) is a protein from Homo sapiens identified by UniProt accession Q8NBI6, 393 residues long. MolForge cross-references it against 0 known binders and 38 disease associations.
- UniProt accession: Q8NBI6; gene symbol XXYLT1.
- Organism: Homo sapiens.
- Length: 393 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, body mass index and body height.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Xyloside xylosyltransferase 1 |
|---|---|
| UniProt accession | Q8NBI6 |
| Gene | XXYLT1 |
| Organism | Homo sapiens |
| Length | 393 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (38)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.44
- body mass index · score 0.31
- body height · score 0.30
- body weight · score 0.29
- blood protein measurement · score 0.25
- non-small cell lung carcinoma · score 0.25
- atrial fibrillation · score 0.22
- erythrocyte count · score 0.18
- hemoglobin measurement · score 0.18
- hematocrit · score 0.18
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8NBI6-F1 | alphafold | PREDICTED | 83.97 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8NBI6.
Amino-acid sequence (393 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with XXYLT1?
The strongest Open Targets associations for XXYLT1 are neurodegenerative disease, body mass index, body height, body weight and blood protein measurement.
How long is the XXYLT1 protein?
The Homo sapiens XXYLT1 protein (UniProt Q8NBI6) is 393 amino acids long.
Browse: Targets: X · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8NBI6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8NBI6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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