SID1 transmembrane family member 2 (SIDT2)
Homo sapiens — UniProt Q8NBJ9
Data last refreshed: (UniProt release unknown)
Key facts
SID1 transmembrane family member 2 (SIDT2) is a protein from Homo sapiens identified by UniProt accession Q8NBJ9, 832 residues long. MolForge cross-references it against 0 known binders and 220 disease associations.
- UniProt accession: Q8NBJ9; gene symbol SIDT2.
- Organism: Homo sapiens.
- Length: 832 amino acids.
- Top disease associations (Open Targets): triglyceride measurement, triglyceride:HDL cholesterol ratio and apolipoprotein A 1 measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | SID1 transmembrane family member 2 |
|---|---|
| UniProt accession | Q8NBJ9 |
| Gene | SIDT2 |
| Organism | Homo sapiens |
| Length | 832 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (220)
Diseases linked to this target (Open Targets).
- triglyceride measurement · score 0.45
- triglyceride:HDL cholesterol ratio · score 0.37
- apolipoprotein A 1 measurement · score 0.24
- body mass index · score 0.20
- monocyte count · score 0.19
- blood protein measurement · score 0.17
- systolic blood pressure · score 0.15
- hypertension · score 0.12
- Calcium channel blocker use measurement · score 0.11
- diastolic blood pressure · score 0.11
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8NBJ9-F1 | alphafold | PREDICTED | 80.25 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8NBJ9.
Amino-acid sequence (832 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SIDT2?
The strongest Open Targets associations for SIDT2 are triglyceride measurement, triglyceride:HDL cholesterol ratio, apolipoprotein A 1 measurement, body mass index and monocyte count.
How long is the SIDT2 protein?
The Homo sapiens SIDT2 protein (UniProt Q8NBJ9) is 832 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8NBJ9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8NBJ9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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