Ubiquitin-associated domain-containing protein 2 (UBAC2)
Homo sapiens — UniProt Q8NBM4
Data last refreshed: (UniProt release unknown)
Key facts
Ubiquitin-associated domain-containing protein 2 (UBAC2) is a protein from Homo sapiens identified by UniProt accession Q8NBM4, 344 residues long. MolForge cross-references it against 0 known binders and 55 disease associations.
- UniProt accession: Q8NBM4; gene symbol UBAC2.
- Organism: Homo sapiens.
- Length: 344 amino acids.
- Top disease associations (Open Targets): eosinophil count, asthma and eosinophil percentage of leukocytes.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ubiquitin-associated domain-containing protein 2 |
|---|---|
| UniProt accession | Q8NBM4 |
| Gene | UBAC2 |
| Organism | Homo sapiens |
| Length | 344 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (55)
Diseases linked to this target (Open Targets).
- eosinophil count · score 0.37
- asthma · score 0.32
- eosinophil percentage of leukocytes · score 0.32
- lymphocyte count · score 0.29
- childhood onset asthma · score 0.28
- Inhalant adrenergic use measurement · score 0.26
- hypothyroidism · score 0.25
- sum of eosinophil and basophil counts · score 0.25
- psoriasis · score 0.24
- inflammatory bowel disease · score 0.23
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8NBM4-F1 | alphafold | PREDICTED | 72.15 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8NBM4.
Amino-acid sequence (344 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with UBAC2?
The strongest Open Targets associations for UBAC2 are eosinophil count, asthma, eosinophil percentage of leukocytes, lymphocyte count and childhood onset asthma.
How long is the UBAC2 protein?
The Homo sapiens UBAC2 protein (UniProt Q8NBM4) is 344 amino acids long.
Browse: Targets: U · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8NBM4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8NBM4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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