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Prenylcysteine oxidase 1-like (PCYOX1L)

Homo sapiens — UniProt Q8NBM8

Gene: PCYOX1LHomo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Prenylcysteine oxidase 1-like (PCYOX1L) is a protein from Homo sapiens identified by UniProt accession Q8NBM8, 494 residues long. MolForge cross-references it against 0 known binders and 18 disease associations.

  • UniProt accession: Q8NBM8; gene symbol PCYOX1L.
  • Organism: Homo sapiens.
  • Length: 494 amino acids.
  • Top disease associations (Open Targets): mean platelet volume, breast adenocarcinoma and body height.
  • 3D structure: AlphaFold model available.

Target properties

Protein namePrenylcysteine oxidase 1-like
UniProt accessionQ8NBM8
GenePCYOX1L
OrganismHomo sapiens
Length494 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (18)

Diseases linked to this target (Open Targets).

  • mean platelet volume · score 0.41
  • breast adenocarcinoma · score 0.25
  • body height · score 0.14
  • deep vein thrombosis · score 0.05
  • vital capacity · score 0.05
  • forced expiratory volume · score 0.03
  • macula measurement · score 0.02
  • infect · score 0.01
  • infection · score 0.01
  • Alzheimer disease · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q8NBM8-F1alphafoldPREDICTED89.83—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8NBM8.

Amino-acid sequence (494 residues)

MARAAPLLAA LTALLAAAAA GGDAPPGKIA VVGAGIGGSA VAHFLQQHFG PRVQIDVYEK GTVGGRLATI SVNKQHYESG AASFHSLSLH MQDFVKLLGL RHRREVVGRS AIFGGEHFML EETDWYLLNL FRLWWHYGIS FLRLQMWVEE VMEKFMRIYK YQAHGYAFSG VEELLYSLGE STFVNMTQHS VAESLLQVGV TQRFIDDVVS AVLRASYGQS AAMPAFAGAM SLAGAQGSLW SVEGGNKLVC SGLLKLTKAN VIHATVTSVT LHSTEGKALY QVAYENEVGN SSDFYDIVVI ATPLHLDNSS SNLTFAGFHP PIDDVQGSFQ PTVVSLVHGY LNSSYFGFPD PKLFPFANIL TTDFPSFFCT LDNICPVNIS ASFRRKQPQE AAVWRVQSPK PLFRTQLKTL FRSYYSVQTA EWQAHPLYGS RPTLPRFALH DQLFYLNALE WAASSVEVMA VAAKNVALLA YNRWYQDLDK IDQKDLMHKV KTEL

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with PCYOX1L?

The strongest Open Targets associations for PCYOX1L are mean platelet volume, breast adenocarcinoma, body height, deep vein thrombosis and vital capacity.

How long is the PCYOX1L protein?

The Homo sapiens PCYOX1L protein (UniProt Q8NBM8) is 494 amino acids long.

Browse: Targets: P · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ8NBM8
GenePCYOX1L
OrganismHomo sapiens
Length494
Binders0
Diseases18
View on UniProt