Retinol dehydrogenase 13 (RDH13)
Homo sapiens — UniProt Q8NBN7
Data last refreshed: (UniProt release unknown)
Key facts
Retinol dehydrogenase 13 (RDH13) is a protein from Homo sapiens identified by UniProt accession Q8NBN7, 331 residues long. MolForge cross-references it against 1 known binders and 24 disease associations.
- UniProt accession: Q8NBN7; gene symbol RDH13.
- Organism: Homo sapiens.
- Length: 331 amino acids.
- Top disease associations (Open Targets): neuroinflammatory disorder, platelet component distribution width and mean platelet volume.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Retinol dehydrogenase 13 |
|---|---|
| UniProt accession | Q8NBN7 |
| Gene | RDH13 |
| Organism | Homo sapiens |
| Length | 331 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (24)
Diseases linked to this target (Open Targets).
- neuroinflammatory disorder · score 0.33
- platelet component distribution width · score 0.20
- mean platelet volume · score 0.20
- platelet glycoprotein VI measurement · score 0.20
- neurodegenerative disease · score 0.17
- blood protein measurement · score 0.14
- Benign familial chorea · score 0.06
- X-linked retinal dysplasia · score 0.05
- reticulocyte count · score 0.03
- neutrophil count · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8NBN7-F1 | alphafold | PREDICTED | 89.31 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8NBN7.
Amino-acid sequence (331 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with RDH13?
The strongest Open Targets associations for RDH13 are neuroinflammatory disorder, platelet component distribution width, mean platelet volume, platelet glycoprotein VI measurement and neurodegenerative disease.
How long is the RDH13 protein?
The Homo sapiens RDH13 protein (UniProt Q8NBN7) is 331 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8NBN7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8NBN7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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