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Tumor protein p53-inducible protein 13 (TP53I13)

Homo sapiens — UniProt Q8NBR0

Gene: TP53I13Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Tumor protein p53-inducible protein 13 (TP53I13) is a protein from Homo sapiens identified by UniProt accession Q8NBR0, 393 residues long. MolForge cross-references it against 0 known binders and 40 disease associations.

  • UniProt accession: Q8NBR0; gene symbol TP53I13.
  • Organism: Homo sapiens.
  • Length: 393 amino acids.
  • Top disease associations (Open Targets): body height, neurodegenerative disease and mean platelet volume.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameTumor protein p53-inducible protein 13
UniProt accessionQ8NBR0
GeneTP53I13
OrganismHomo sapiens
Length393 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (40)

Diseases linked to this target (Open Targets).

  • body height · score 0.28
  • neurodegenerative disease · score 0.26
  • mean platelet volume · score 0.16
  • fat body mass · score 0.11
  • BMI-adjusted hip circumference · score 0.11
  • sitting height measurement · score 0.09
  • high density lipoprotein cholesterol measurement · score 0.08
  • triglyceride measurement · score 0.08
  • neoplasm · score 0.08
  • mitochondrial DNA measurement · score 0.06

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q8NBR0-F1alphafoldPREDICTED60.73—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8NBR0.

Amino-acid sequence (393 residues)

MAPPPPSPQL LLLAALARLL GPSEVMAGPA EEAGAHCPES LWPLPPQVSP RVTYTRVSPG QAEDVTFLYH PCAHPWLKLQ LALLAYACMA NPSLTPDFSL TQDRPLVLTA WGLALEMAWV EPAWAAHWLM RRRRRKQRKK KAWIYCESLS GPAPSEPTPG RGRLCRRGCV QALALAFALR SWRPPGTEVT SQGPRQPSSS GAKRRRLRAA LGPQPTRSAL RFPSASPGSL KAKQSMAGIP GRESNAPSVP TVSLLPGAPG GNASSRTEAQ VPNGQGSPGG CVCSSQASPA PRAAAPPRAA RGPTPRTEEA AWAAMALTFL LVLLTLATLC TRLHRNFRRG ESIYWGPTAD SQDTVAAVLK RRLLQPSRRV KRSRRRPLLP PTPDSGPEGE SSE

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with TP53I13?

The strongest Open Targets associations for TP53I13 are body height, neurodegenerative disease, mean platelet volume, fat body mass and BMI-adjusted hip circumference.

How long is the TP53I13 protein?

The Homo sapiens TP53I13 protein (UniProt Q8NBR0) is 393 amino acids long.

Browse: Targets: T · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ8NBR0
GeneTP53I13
OrganismHomo sapiens
Length393
Binders0
Diseases40
View on UniProt