Saccharopine dehydrogenase-like oxidoreductase (SCCPDH)
Homo sapiens — UniProt Q8NBX0
Data last refreshed: (UniProt release unknown)
Key facts
Saccharopine dehydrogenase-like oxidoreductase (SCCPDH) is a protein from Homo sapiens identified by UniProt accession Q8NBX0, 429 residues long. MolForge cross-references it against 0 known binders and 114 disease associations.
- UniProt accession: Q8NBX0; gene symbol SCCPDH.
- Organism: Homo sapiens.
- Length: 429 amino acids.
- Top disease associations (Open Targets): mean platelet volume, age at menopause and apolipoprotein B measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Saccharopine dehydrogenase-like oxidoreductase |
|---|---|
| UniProt accession | Q8NBX0 |
| Gene | SCCPDH |
| Organism | Homo sapiens |
| Length | 429 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (114)
Diseases linked to this target (Open Targets).
- mean platelet volume · score 0.35
- age at menopause · score 0.32
- apolipoprotein B measurement · score 0.27
- breast adenocarcinoma · score 0.25
- esophageal cancer · score 0.12
- Romano-Ward syndrome · score 0.06
- Brugada syndrome · score 0.06
- familial atrial fibrillation · score 0.06
- azoospermia · score 0.06
- Familial short QT syndrome · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8NBX0-F1 | alphafold | PREDICTED | 94.74 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8NBX0.
Amino-acid sequence (429 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SCCPDH?
The strongest Open Targets associations for SCCPDH are mean platelet volume, age at menopause, apolipoprotein B measurement, breast adenocarcinoma and esophageal cancer.
How long is the SCCPDH protein?
The Homo sapiens SCCPDH protein (UniProt Q8NBX0) is 429 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8NBX0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8NBX0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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