RELT-like protein 2 (RELL2)
Homo sapiens — UniProt Q8NC24
Data last refreshed: (UniProt release unknown)
Key facts
RELT-like protein 2 (RELL2) is a protein from Homo sapiens identified by UniProt accession Q8NC24, 303 residues long. MolForge cross-references it against 0 known binders and 23 disease associations.
- UniProt accession: Q8NC24; gene symbol RELL2.
- Organism: Homo sapiens.
- Length: 303 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, refractive error measurement and neoplasm.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | RELT-like protein 2 |
|---|---|
| UniProt accession | Q8NC24 |
| Gene | RELL2 |
| Organism | Homo sapiens |
| Length | 303 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (23)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.51
- refractive error measurement · score 0.18
- neoplasm · score 0.08
- cancer · score 0.08
- body mass index · score 0.06
- mathematical ability · score 0.05
- mean platelet volume · score 0.04
- age at first birth measurement · score 0.03
- glioblastoma multiforme · score 0.02
- pancreatic adenocarcinoma · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8NC24-F1 | alphafold | PREDICTED | 59.09 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8NC24.
Amino-acid sequence (303 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with RELL2?
The strongest Open Targets associations for RELL2 are neurodegenerative disease, refractive error measurement, neoplasm, cancer and body mass index.
How long is the RELL2 protein?
The Homo sapiens RELL2 protein (UniProt Q8NC24) is 303 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8NC24 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8NC24 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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