RBBP8 N-terminal-like protein (RBBP8NL)
Homo sapiens — UniProt Q8NC74
Data last refreshed: (UniProt release unknown)
Key facts
RBBP8 N-terminal-like protein (RBBP8NL) is a protein from Homo sapiens identified by UniProt accession Q8NC74, 664 residues long. MolForge cross-references it against 0 known binders and 23 disease associations.
- UniProt accession: Q8NC74; gene symbol RBBP8NL.
- Organism: Homo sapiens.
- Length: 664 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, prostate carcinoma and FEV/FVC ratio.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | RBBP8 N-terminal-like protein |
|---|---|
| UniProt accession | Q8NC74 |
| Gene | RBBP8NL |
| Organism | Homo sapiens |
| Length | 664 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (23)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.22
- prostate carcinoma · score 0.17
- FEV/FVC ratio · score 0.17
- hemoglobin measurement · score 0.15
- erythrocyte count · score 0.13
- hematocrit · score 0.10
- brain volume measurement · score 0.08
- neuroimaging measurement · score 0.07
- atrial fibrillation · score 0.06
- brain stem volume measurement · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8NC74-F1 | alphafold | PREDICTED | 54.77 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8NC74.
Amino-acid sequence (664 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with RBBP8NL?
The strongest Open Targets associations for RBBP8NL are neurodegenerative disease, prostate carcinoma, FEV/FVC ratio, hemoglobin measurement and erythrocyte count.
How long is the RBBP8NL protein?
The Homo sapiens RBBP8NL protein (UniProt Q8NC74) is 664 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8NC74 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8NC74 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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