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Zinc finger protein 784 (ZNF784)

Homo sapiens — UniProt Q8NCA9

Gene: ZNF784Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Zinc finger protein 784 (ZNF784) is a protein from Homo sapiens identified by UniProt accession Q8NCA9, 323 residues long. MolForge cross-references it against 0 known binders and 7 disease associations.

  • UniProt accession: Q8NCA9; gene symbol ZNF784.
  • Organism: Homo sapiens.
  • Length: 323 amino acids.
  • Top disease associations (Open Targets): insomnia measurement, neurodegenerative disease and high density lipoprotein cholesterol measurement.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameZinc finger protein 784
UniProt accessionQ8NCA9
GeneZNF784
OrganismHomo sapiens
Length323 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (7)

Diseases linked to this target (Open Targets).

  • insomnia measurement · score 0.26
  • neurodegenerative disease · score 0.20
  • high density lipoprotein cholesterol measurement · score 0.03
  • COVID-19 · score 0.02
  • secondary progressive multiple sclerosis · score 0.01
  • in situ carcinoma · score 0.00
  • achalasia-alacrima syndrome · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q8NCA9-F1alphafoldPREDICTED63.37—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8NCA9.

Amino-acid sequence (323 residues)

MAAARPEAQS RSSPTPESRS QEPLDLVLVP DDCRPGTPPS DLIEIQVVKV TDTTLVPEPP EPGSFHCALC PAAFRLVSEL LFHEHGHLAG AEGGGQGGDP SRCHVCGHSC PGPASLRAHY SLHTGERPYR CALCPRAFKA LAPLLRHQHR HGVEPGTSRR PPDTAAVAEQ RPGVAPERAE VVMAAAAAGA AVGKPFACRF CAKPFRRSSD MRDHERVHTG ERPYHCGICG KGFTQSSVLS GHARIHTGER PFRCTLCDRT FNNSSNFRKH QRTHFHGPGP GLGDSGGQLG SSAAEGSGSG CGVGDPAEEG RGETAKVKVE ADQ

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with ZNF784?

The strongest Open Targets associations for ZNF784 are insomnia measurement, neurodegenerative disease, high density lipoprotein cholesterol measurement, COVID-19 and secondary progressive multiple sclerosis.

How long is the ZNF784 protein?

The Homo sapiens ZNF784 protein (UniProt Q8NCA9) is 323 amino acids long.

Browse: Targets: Z · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ8NCA9
GeneZNF784
OrganismHomo sapiens
Length323
Binders0
Diseases7
View on UniProt