Zinc finger protein 485 (ZNF485)
Homo sapiens — UniProt Q8NCK3
Data last refreshed: (UniProt release unknown)
Key facts
Zinc finger protein 485 (ZNF485) is a protein from Homo sapiens identified by UniProt accession Q8NCK3, 441 residues long. MolForge cross-references it against 0 known binders and 21 disease associations.
- UniProt accession: Q8NCK3; gene symbol ZNF485.
- Organism: Homo sapiens.
- Length: 441 amino acids.
- Top disease associations (Open Targets): body height, neurodegenerative disease and acute myeloid leukemia.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc finger protein 485 |
|---|---|
| UniProt accession | Q8NCK3 |
| Gene | ZNF485 |
| Organism | Homo sapiens |
| Length | 441 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (21)
Diseases linked to this target (Open Targets).
- body height · score 0.39
- neurodegenerative disease · score 0.34
- acute myeloid leukemia · score 0.18
- coronary artery disease · score 0.13
- myocardial infarction · score 0.13
- heel bone mineral density · score 0.12
- cortical surface area measurement · score 0.10
- angina pectoris · score 0.10
- coronary artery bypass · score 0.10
- brain measurement · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8NCK3-F1 | alphafold | PREDICTED | 78.80 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8NCK3.
Amino-acid sequence (441 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZNF485?
The strongest Open Targets associations for ZNF485 are body height, neurodegenerative disease, acute myeloid leukemia, coronary artery disease and myocardial infarction.
How long is the ZNF485 protein?
The Homo sapiens ZNF485 protein (UniProt Q8NCK3) is 441 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8NCK3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8NCK3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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